SABRI is the first non-government, non-profit medical research organization established in South Africa. It is a supported largely by the private sector through donations, mainly from big corporations, who see this as part of their social responsibility. The MRC (South African Medical Research Council) and NRF (National Research Foundation) have also provided funding. The institute is devoted to investigating brain function in health and disease. Since its inception in 1982, the Institute has been involved in researching the endorphin system, using psychotropic analgesic nitrous oxide (PAN) as a neurophysiological probe. An area of research which has already produced tangible practical results, apart from pure scientific findings. SABRI scientists, have discovered the most rapid, safe and effective treatment for acute addictive withdrawal states using PAN. When PAN is employed for this purpose it offers distinct advantages for treating the most common substances of abuse including heroin, cannabis, alcohol, nicotine, benzodiazepines and cocaine.

SABRI is particularly interested in doing collaborative studies with using PAN for treating substance abuse. The Institute therefore invites interested scientists to spend some time at SABRI and its affiliated clinics (throughout South Africa), doing collaborative research. Funding for such visits would have to be obtained by the visitor from sources available to him/her, or their institution. Work with PAN lends itself to exciting dissertation possibilities, as the field is largely untapped. Already, five postgraduate dissertations on PAN have resulted in postgraduate degrees. And these have merely scratched the surface of this fertile and intriguing area of investigation. Information about collaboration and/or the necessary training for undertaking further trials or clinical work with PAN can be obtained by contacting SABRI.

Training can be arranged in South Africa or anywhere else in the world.



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